![Zoledronic Acid Activates the DNA S-Phase Checkpoint and Induces Osteosarcoma Cell Death Characterized by Apoptosis-Inducing Factor and Endonuclease-G Translocation Independently of p53 and Retinoblastoma Status | Molecular Pharmacology Zoledronic Acid Activates the DNA S-Phase Checkpoint and Induces Osteosarcoma Cell Death Characterized by Apoptosis-Inducing Factor and Endonuclease-G Translocation Independently of p53 and Retinoblastoma Status | Molecular Pharmacology](https://molpharm.aspetjournals.org/content/molpharm/71/1/333/F7.large.jpg)
Zoledronic Acid Activates the DNA S-Phase Checkpoint and Induces Osteosarcoma Cell Death Characterized by Apoptosis-Inducing Factor and Endonuclease-G Translocation Independently of p53 and Retinoblastoma Status | Molecular Pharmacology
![Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. | Semantic Scholar Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/366a9fa21911215bb089ce369250ff1587f47dbd/36-Figure9-1.png)
Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. | Semantic Scholar
![Efficacy and safety of continued zoledronic acid every 4 weeks versus every 12 weeks in women with bone metastases from breast cancer Results of the OPTIMIZE-2 trial – OncoPrescribe Efficacy and safety of continued zoledronic acid every 4 weeks versus every 12 weeks in women with bone metastases from breast cancer Results of the OPTIMIZE-2 trial – OncoPrescribe](http://www.oncoprescribe.com/app/uploads/_1406171985.jpg)
Efficacy and safety of continued zoledronic acid every 4 weeks versus every 12 weeks in women with bone metastases from breast cancer Results of the OPTIMIZE-2 trial – OncoPrescribe
![Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment? | Breast Cancer Research | Full Text Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment? | Breast Cancer Research | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fbcr3223/MediaObjects/13058_2012_3048_Fig1_HTML.jpg)
Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment? | Breast Cancer Research | Full Text
![Mechanism of action of abiraterone acetate, enzalutamide, radium-223... | Download Scientific Diagram Mechanism of action of abiraterone acetate, enzalutamide, radium-223... | Download Scientific Diagram](https://www.researchgate.net/publication/324912322/figure/fig4/AS:865472643862537@1583356166698/Mechanism-of-action-of-abiraterone-acetate-enzalutamide-radium-223-dichloride.png)
Mechanism of action of abiraterone acetate, enzalutamide, radium-223... | Download Scientific Diagram
![The role of bisphosphonates in multiple myeloma: mechanisms, side effects, and the future. | Semantic Scholar The role of bisphosphonates in multiple myeloma: mechanisms, side effects, and the future. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/02ae3788787adf6a230ad8aee9e0cf256fd0f00b/2-Figure1-1.png)
The role of bisphosphonates in multiple myeloma: mechanisms, side effects, and the future. | Semantic Scholar
![Cancers | Free Full-Text | Osteoporosis: A Long-Term and Late-Effect of Breast Cancer Treatments | HTML Cancers | Free Full-Text | Osteoporosis: A Long-Term and Late-Effect of Breast Cancer Treatments | HTML](https://www.mdpi.com/cancers/cancers-12-03094/article_deploy/html/images/cancers-12-03094-g001.png)
Cancers | Free Full-Text | Osteoporosis: A Long-Term and Late-Effect of Breast Cancer Treatments | HTML
![Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: a brief review | BMC Cancer | Full Text Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: a brief review | BMC Cancer | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12885-020-07568-9/MediaObjects/12885_2020_7568_Fig3_HTML.png)
Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: a brief review | BMC Cancer | Full Text
![Mechanism of action of denosumab compared to zoledronic acid. Notes:... | Download Scientific Diagram Mechanism of action of denosumab compared to zoledronic acid. Notes:... | Download Scientific Diagram](https://www.researchgate.net/profile/Andrew-Yee-7/publication/230850646/figure/fig1/AS:202882147196929@1425382281783/Mechanism-of-action-of-denosumab-compared-to-zoledronic-acid-Notes-RANKL-is-secreted-by_Q640.jpg)
Mechanism of action of denosumab compared to zoledronic acid. Notes:... | Download Scientific Diagram
![Development of zoledronic acid functionalized hydroxyapatite loaded polymeric nanoparticles for the treatment of osteoporosis Development of zoledronic acid functionalized hydroxyapatite loaded polymeric nanoparticles for the treatment of osteoporosis](https://www.spandidos-publications.com/article_images/etm/16/2/etm-16-02-0704-g02.jpg)
Development of zoledronic acid functionalized hydroxyapatite loaded polymeric nanoparticles for the treatment of osteoporosis
![Possible ocular adverse effects attributable to bisphosphonate therapy: Two case reports | Revista Colombiana de Reumatología (English Edition) Possible ocular adverse effects attributable to bisphosphonate therapy: Two case reports | Revista Colombiana de Reumatología (English Edition)](https://multimedia.elsevier.es/PublicationsMultimediaV1/item/multimedia/S2444440517300274:gr1.jpeg?xkr=ue/ImdikoIMrsJoerZ+w997EogCnBdOOD93cPFbanNc1SMvz46gXX2zWoVNOOjrSTwdN3jKSy8lwLSDyjyDlrMClK15O8Mmd01j+kn7NA+NH9QXa7K4ey/Rqh70O9B39o57t3RZQc8r9gps9ZliwnuhnTo5ExeaYRj/HhH6d2RQWo4BGGqYbmDD/ULNpaxlTWqg4fhuw18QNPpM+9YkwSzy635OyeKndIRgjR7e4mGZVYfszHglOCKmKkfTpt6QgAVIbKYJAIrKEfVP3qDu/JEjWtY0pYaX+/iLeXcsq+oY=)
Possible ocular adverse effects attributable to bisphosphonate therapy: Two case reports | Revista Colombiana de Reumatología (English Edition)
![Cureus | Comparing the Efficacy and Safety of Denosumab with Bisphosphonates in Increasing Bone Mineral Density in Patients with Prostate Cancer and Breast Cancer on Antihormonal Treatment Cureus | Comparing the Efficacy and Safety of Denosumab with Bisphosphonates in Increasing Bone Mineral Density in Patients with Prostate Cancer and Breast Cancer on Antihormonal Treatment](https://assets.cureus.com/uploads/figure/file/90324/lightbox_56873fb01c7f11ea967fe109aa9b495a-Figure-2_formatted_V1-PME.png)
Cureus | Comparing the Efficacy and Safety of Denosumab with Bisphosphonates in Increasing Bone Mineral Density in Patients with Prostate Cancer and Breast Cancer on Antihormonal Treatment
![ZOMETA (zoledronic acid) for Hypercalcemia of Malignancy and Bone Metastases - Cancer Therapy Advisor ZOMETA (zoledronic acid) for Hypercalcemia of Malignancy and Bone Metastases - Cancer Therapy Advisor](https://www.cancertherapyadvisor.com/wp-content/uploads/sites/12/2018/12/slide12111_1053447.jpg)