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Overall Survival Benefit is Seen with Olaparib in Patients with Ovarian Cancer and TP53 Disruptive Mutation Status | ESMO
![Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models | Nature Communications Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-020-17127-2/MediaObjects/41467_2020_17127_Fig1_HTML.png)
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models | Nature Communications
![SOLO-1 Phase III trial demonstrates Lynparza maintenance therapy cut risk of disease progression or death by 70% in patients with newly-diagnosed, advanced BRCA-mutated ovarian cancer SOLO-1 Phase III trial demonstrates Lynparza maintenance therapy cut risk of disease progression or death by 70% in patients with newly-diagnosed, advanced BRCA-mutated ovarian cancer](https://www.astrazeneca.com/content/dam/az/media-centre-docs/press-releases/2018/Kaplan.png/_jcr_content/renditions/cq5dam.web.320.Kaplan.png)
SOLO-1 Phase III trial demonstrates Lynparza maintenance therapy cut risk of disease progression or death by 70% in patients with newly-diagnosed, advanced BRCA-mutated ovarian cancer
![LYNPARZA® (olaparib) First-Line Maintenance Therapy Nearly Doubled the Time Without Disease Progression or Death in Phase 3 POLO Trial for Patients with Germline BRCA-Mutated Metastatic Pancreatic Cancer | BioSpace LYNPARZA® (olaparib) First-Line Maintenance Therapy Nearly Doubled the Time Without Disease Progression or Death in Phase 3 POLO Trial for Patients with Germline BRCA-Mutated Metastatic Pancreatic Cancer | BioSpace](https://mms.businesswire.com/media/20190602005064/en/725003/4/POLO_KM_Curve.jpg)
LYNPARZA® (olaparib) First-Line Maintenance Therapy Nearly Doubled the Time Without Disease Progression or Death in Phase 3 POLO Trial for Patients with Germline BRCA-Mutated Metastatic Pancreatic Cancer | BioSpace
![Prognostic nomogram for progression-free survival in patients with BRCA mutations and platinum-sensitive recurrent ovarian cancer on maintenance olaparib therapy following response to chemotherapy - European Journal of Cancer Prognostic nomogram for progression-free survival in patients with BRCA mutations and platinum-sensitive recurrent ovarian cancer on maintenance olaparib therapy following response to chemotherapy - European Journal of Cancer](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/0f0fa4cb-7ea2-40cc-8a84-b5494de22776/gr1_lrg.jpg)
Prognostic nomogram for progression-free survival in patients with BRCA mutations and platinum-sensitive recurrent ovarian cancer on maintenance olaparib therapy following response to chemotherapy - European Journal of Cancer
![Olaparib maintenance therapy in platinum-sensitive relapsed ovarian... | Download Scientific Diagram Olaparib maintenance therapy in platinum-sensitive relapsed ovarian... | Download Scientific Diagram](https://www.researchgate.net/publication/307515666/figure/fig2/AS:401297061761031@1472688084030/Olaparib-maintenance-therapy-in-platinum-sensitive-relapsed-ovarian-cancer.png)
Olaparib maintenance therapy in platinum-sensitive relapsed ovarian... | Download Scientific Diagram
![Tolerability of maintenance olaparib in newly diagnosed patients with advanced ovarian cancer and a BRCA mutation in the randomized phase III SOLO1 trial - Gynecologic Oncology Tolerability of maintenance olaparib in newly diagnosed patients with advanced ovarian cancer and a BRCA mutation in the randomized phase III SOLO1 trial - Gynecologic Oncology](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/be841181-0262-4558-8872-4faa1f190d4d/gr1_lrg.jpg)
Tolerability of maintenance olaparib in newly diagnosed patients with advanced ovarian cancer and a BRCA mutation in the randomized phase III SOLO1 trial - Gynecologic Oncology
![SGO on Twitter: "Olaparib maintenance therapy improves overall survival in recurrent #ovariancancer - important update of the SOLO2 trial at #ASCO20 #SGOatASCO #gyncsm https://t.co/xX2D6nyErE" / Twitter SGO on Twitter: "Olaparib maintenance therapy improves overall survival in recurrent #ovariancancer - important update of the SOLO2 trial at #ASCO20 #SGOatASCO #gyncsm https://t.co/xX2D6nyErE" / Twitter](https://pbs.twimg.com/media/EZR_4VYXQAcQZDp.jpg)
SGO on Twitter: "Olaparib maintenance therapy improves overall survival in recurrent #ovariancancer - important update of the SOLO2 trial at #ASCO20 #SGOatASCO #gyncsm https://t.co/xX2D6nyErE" / Twitter
![PARP inhibitor (olaparib) dramaticalyl extends progression free survival in 1L Maintenance BRCAm ovarian cancer data. Hazard ratio = 0.30. : r/medicine PARP inhibitor (olaparib) dramaticalyl extends progression free survival in 1L Maintenance BRCAm ovarian cancer data. Hazard ratio = 0.30. : r/medicine](https://i.redd.it/c4fs52en4kt11.png)
PARP inhibitor (olaparib) dramaticalyl extends progression free survival in 1L Maintenance BRCAm ovarian cancer data. Hazard ratio = 0.30. : r/medicine
![Overall survival and updated progression-free survival outcomes in a randomized phase II study of combination cediranib and olaparib versus olaparib in relapsed platinum-sensitive ovarian cancer - Annals of Oncology Overall survival and updated progression-free survival outcomes in a randomized phase II study of combination cediranib and olaparib versus olaparib in relapsed platinum-sensitive ovarian cancer - Annals of Oncology](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/86050a72-7c80-44a2-9718-35ae46199b3d/gr3.jpg)
Overall survival and updated progression-free survival outcomes in a randomized phase II study of combination cediranib and olaparib versus olaparib in relapsed platinum-sensitive ovarian cancer - Annals of Oncology
![Predictors of progression free survival, overall survival and early cessation of chemotherapy in women with potentially platinum sensitive (PPS) recurrent ovarian cancer (ROC) starting third or subsequent line(≥3) chemotherapy – The GCIG Predictors of progression free survival, overall survival and early cessation of chemotherapy in women with potentially platinum sensitive (PPS) recurrent ovarian cancer (ROC) starting third or subsequent line(≥3) chemotherapy – The GCIG](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/777aed96-2700-46bf-9ad6-0c159601b8bf/gr1a.jpg)
Predictors of progression free survival, overall survival and early cessation of chemotherapy in women with potentially platinum sensitive (PPS) recurrent ovarian cancer (ROC) starting third or subsequent line(≥3) chemotherapy – The GCIG
![Study 19: final overall survival in all patients and according to BRCAm... | Download Scientific Diagram Study 19: final overall survival in all patients and according to BRCAm... | Download Scientific Diagram](https://www.researchgate.net/publication/333265875/figure/fig1/AS:761348506013698@1558531037293/Study-19-final-overall-survival-in-all-patients-and-according-to-BRCAm-status-a-OS-in_Q640.jpg)
Study 19: final overall survival in all patients and according to BRCAm... | Download Scientific Diagram
![Study 19: final overall survival in all patients and according to BRCAm... | Download Scientific Diagram Study 19: final overall survival in all patients and according to BRCAm... | Download Scientific Diagram](https://www.researchgate.net/publication/333265875/figure/fig1/AS:761348506013698@1558531037293/Study-19-final-overall-survival-in-all-patients-and-according-to-BRCAm-status-a-OS-in.png)
Study 19: final overall survival in all patients and according to BRCAm... | Download Scientific Diagram
![Overall survival and updated progression-free survival outcomes in a randomized phase II study of combination cediranib and olaparib versus olaparib in relapsed platinum-sensitive ovarian cancer - Annals of Oncology Overall survival and updated progression-free survival outcomes in a randomized phase II study of combination cediranib and olaparib versus olaparib in relapsed platinum-sensitive ovarian cancer - Annals of Oncology](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/cb0a8ee1-87ff-44c3-8fdf-f28752261a79/gr1_lrg.jpg)
Overall survival and updated progression-free survival outcomes in a randomized phase II study of combination cediranib and olaparib versus olaparib in relapsed platinum-sensitive ovarian cancer - Annals of Oncology
![JCM | Free Full-Text | Real-World Experience of Olaparib Maintenance in High-Grade Serous Recurrent Ovarian Cancer Patients with BRCA1/2 Mutation: A Korean Multicenter Study | HTML JCM | Free Full-Text | Real-World Experience of Olaparib Maintenance in High-Grade Serous Recurrent Ovarian Cancer Patients with BRCA1/2 Mutation: A Korean Multicenter Study | HTML](https://www.mdpi.com/jcm/jcm-08-01920/article_deploy/html/images/jcm-08-01920-g001-550.jpg)