Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer
Pevonedistat - an overview | ScienceDirect Topics
Anticancer drug discovery by targeting cullin neddylation - ScienceDirect
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma | Journal of Experimental & Clinical Cancer Research | Full Text
The NAE inhibitor pevonedistat (MLN4924) synergizes with TNF-α to activate apoptosis | Cell Death Discovery
Celecoxib Synergistically Enhances MLN4924-Induced Cytotoxicity and EMT Inhibition Via AKT and ERK Pathways in Human Urothelial Carcinoma - Shida Xiong, Wei Huang, Xiaoqiang Liu, Qian Chen, Yi Ding, Haoxuan Huang, Ru Zhang,
Working model. Inhibition of neddylation pathway with MLN4924... | Download Scientific Diagram
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Mechanism of MLN4924 action. Proposed mechanisms of how MLN4924... | Download Scientific Diagram
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1 - ScienceDirect
Neddylation regulation of mitochondrial structure and functions | Cell & Bioscience | Full Text
Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy | Cell Death Discovery
Frontiers | Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy
Figure 5 | Targeting the Neddylation Pathway to Suppress the Growth of Prostate Cancer Cells: Therapeutic Implication for the Men's Cancer
Continued ) F, schematic illustration of proposed mechanism underlying... | Download Scientific Diagram
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
Frontiers | Advances in Cancer Treatment by Targeting the Neddylation Pathway
The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation - ScienceDirect
Pevonedistat - an overview | ScienceDirect Topics
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib
