Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1 | Journal of Medicinal Chemistry
Suicide Substrate - an overview | ScienceDirect Topics
Andrew Murkin on Twitter: "Covalent inhibition is all the rage these days! Check out our Perspective in @BiochemistryACS highlighting recent advances in mechanism-based and targeted covalent inhibitor design. @CovalentMod @UBChemistry https://t.co ...
Structural Biochemistry/Enzyme/Suicide Inhibitors - Wikibooks, open books for an open world
Mechanism-based inhibition of the melatonin rhythm enzyme: Pharmacologic exploitation of active site functional plasticity | PNAS
Enzyme Inhibition There are several motivations to study enzyme inhibition: Distinguish among the different potential mechanisms in multisubstrate reactions. - ppt download
Mechanism-based inhibition of the melatonin rhythm enzyme: Pharmacologic exploitation of active site functional plasticity | PNAS
PLOS ONE: A quantitative systems pharmacology approach, incorporating a novel liver model, for predicting pharmacokinetic drug-drug interactions
Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, “selectivity pocket” and NAD+-binding site - Chemical Science (RSC Publishing)
ENZYMES Part 2 Ms Rahinaz Department of Biochemistry
Mechanism-based inhibition of cytochrome P450 by methylenedioxyphenyl... | Download Scientific Diagram
Metabolism-Based Drug Interactions | SpringerLink
Underlying mechanism of drug–drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8 - ScienceDirect
Nature Medicine on Twitter: "Mechanism-based small-molecule inhibitors targeting a #gutmicrobe enzyme lower circulating levels of the prothrombotic metabolite trimethylamine-N-oxide and suppress diet-induced #thrombosis in mice: https://t.co/hSRuZORjQI ...
Mechanism-based design of a protein kinase inhibitor | Nature Structural & Molecular Biology
Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies - Chemical Science (RSC Publishing)
Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. | Semantic Scholar
Ch 3: Mechanisms of Enzyme Inhibition - ppt download
Inhibitory kinetics of fruit components on CYP2C19 activity - ScienceDirect
A-B) Lead structure for the mechanism-based suicide-inhibitor of... | Download Scientific Diagram
l-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5′-phosphate-thiazolidine adduct - MedChemComm (RSC Publishing)
Simple kinetics of mechanism-based inhibitors and "suicide substrates". | Download Scientific Diagram
